Tuesday, April 14, 2020

Structural Bioinformatics Tools for Drug Design - Extraction of Biologically Relevant Information from Structural Databases (Bookzcity)





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This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made.

The rise of computers has revolutionized every single field of human activity. Medicine and drug design is no exception. In fact, understanding the basis of different diseases together with the development of appropriate cures has taken a gigantic leapforwardinthelastfewdecades.Inthepast,drugdesignwasmainlythedomain of chemists and medical doctors carrying out wet lab experiments and subsequent testing on live subjects. Nowadays, it is a complicated synergy of a vast spectra of different interoperable life-science fields combined with available biological data. Every day we take advantage of available computational power and combine it with knowledge of the disease’s biological nature in order to grasp its true molecular basis and try to suggest potential drug substances using up-to-date bioinformatics methods.



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